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Sunderland Joint Formulary
NHS Sunderland Clinical Commissioning Group
South Tyneside and Sunderland NHS Foundation Trust
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 Formulary Chapter 8: Malignant disease and immunosuppression - Full Chapter
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08.02.04  Expand sub section  Other immunomodulating drugs
08.02.04  Expand sub section  Interferon Alfa
08.02.04  Expand sub section  Interferon beta
Interferon beta-1a
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Formulary
Red

Prefilled pen (Avonex): 30 micrograms (6 million units)
Prefilled pen (Rebif): 22 microgram (6 million units) & 44 microgram (12 million units)
Cartridge for use in rebismart device: 22 microgram per 0.5ml and 44 microgram per 0.5ml
Prefilled pen: 44 microgram per 0.5ml (Rebidose)
-approved for use when the cartridges and prefilled syringes are unsuitable.

 
   
Interferon beta-1b
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Formulary
Red

Vials for preparing 750 microgram in 3ml injection (Betaferon)
Vials for preparing 250 microgram in 1ml injection (Extavia)

 
   
Peginterferon beta-1a
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Formulary
Red

Prefilled pen: 125 microgram (Plegridy)

 
Link  NICE TA624:Peginterferon beta-1a for treating relapsing–remitting multiple sclerosis
   
08.02.04  Expand sub section  Aldesleukin
08.02.04  Expand sub section  Glatiramer acetate to top
08.02.04  Expand sub section  Natalizumab
 ....
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
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Link to adult BNF
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Link to SPCs
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
NHSE
NHS England
Homecare
Homecare
CCG
CCG

Traffic Light Status Information

Status Description

Red

Drugs for hospital use or use by a specialist within specialist centre only. Initiation and monitoring of treatment should remain under the total responsibility of the appropriate hospital clinician or specialist. These drugs should only be prescribed under the direct supervision of that clinician or specialist and are not suitable for shared care arrangements. The drug should be supplied via the hospital or specialist centre for the duration of treatment.   

Amber

These are specialist drugs which must be initiated by secondary care specialist prescribers, but with the potential to transfer prescribing to primary care within written and agreed shared care protocols and according to the agreed process for transfer of care. For these drugs, in order to ensure patient safety, some aspects of care must remain with the specialist due to their complexity e.g. monitoring of disease or drug response. Other more routine aspects can be transferred to the GP e.g. monitoring of adverse effects and supply of the medicine. The specific responsibilities of the specialist and GP are defined in the shared care agreement for each drug. Shared care agreements are still under development for some amber drugs. Until these are available, it would be expected that any shared care request from secondary care to a GP would be accompanied by written information which defines prescribing and monitoring responsibilities. The hospital specialist should also provide the GP with enough information and support to allow the safe transfer and ongoing management of prescribing into primary care.   

Green +

Drugs which should usually be initiated in secondary care, or by a specialist clinician, but can be safely maintained in primary care with very little or no monitoring required. In some cases there may be a further restriction for use outlined - these will be defined in each case.  

Green

These are defined as new and established drugs, which may be prescribed, initiated, changed or maintained on FP10 by the GP and, if appropriate, discontinued without recourse to secondary care. N.B. DRUGS NOT IDENTIFIED IN THE FORMULARY BY A RED, AMBER OR GREEN+ SYMBOL ARE CLASSIFIED AS GREEN.   

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