North East and North Cumbria
ICS Formulary
 
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5 Infections
05-03-03-02 Chronic hepatitis C & hepatitis D

Daclatasvir
Formulary

  • Approved for the treatment of chronic hepatitis C in line with NICE and NHS England Commissioning Policy.  


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Elbasvir & grazoprevir Zepatier®
Formulary

  • Approved for the treatment of chronic hepatitis C in line with NICE and NHS England Commissioning Policy.

Link  NICE TA413: Elbasvir–grazoprevir for treating chronic hepatitis C

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Glecaprevir & Pibrentasvir Maviret®
Formulary

  • Approved for the treatment of chronic hepatitis C in line with NICE and NHS England Commissioning Policy.

Link  NICE TA499: Glecaprevir–pibrentasvir for treating chronic hepatitis C

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Peginterferon Alfa Pegasys®, ViraferonPeg®
Formulary
  • Approved  for hepatitis B and C in accordance with NICE guidelines and NHS England Commissioning Policies. 

 

  • See Section 08.02.04

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Ribavirin
Formulary
Link  NICE TA106: Hepatitis C - peginterferon alfa and ribavirin
Link  NICE TA200: Hepatitis C - peginterferon alfa and ribavirin
Link  NICE TA75: Hepatitis C - pegylated interferons, ribavirin and alfa interferon

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Sofosbuvir Sovaldi®
Formulary

 

    • Approved for the treatment of chronic hepatitis C in line with NICE and NHS England Commissioning Policy.

 

Link  NICE TA330: Sofosbuvir for treating chronic hepatitis C

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Sofosbuvir & Ledipasvir  Harvoni®
Formulary

  • To be used in accordance with NHS England Commissiong Policy  

Link  NICE TAG63: Ledipasvir–sofosbuvir for treating chronic hepatitis C

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Sofosbuvir & velpatasvir  Epclusa®
Formulary

  • Approved for the treatment of chronic hepatitis C in line with NICE and NHS England Commissioning Policy.

Link  NICE TA430: Sofosbuvir–velpatasvir for treating chronic hepatitis C

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Sofosbuvir, Velpatasvir & Voxilaprevir  Vosevi®
Formulary

  • Approved for the treatment of chronic hepatitis C in line with NICE and NHS England Commissioning Policy.

Link  NICE TA507: Sofosbuvir–velpatasvir–voxilaprevir for treating chronic hepatitis C

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Bulevirtide Hepcludex®
Formulary
  • 2mg powder for solution for injection
  • Approved as an option for treating chronic hepatitis D in adults with compensated liver disease in line with NICE and NHSE Specialised Commissioning Policy only if:
    • there is evidence of significant fibrosis (METAVIR stage F2 or above or Ishak stage 3 or above) and
    • their hepatitis has not responded to peginterferon alfa‑2a (PEG‑IFN) or they cannot have interferon-based therapy
  • Only available from:
    • The Newcastle Upon Tyne Hospitals NHS Foundation trust
Link  NICE TA896: Bulevirtide for treating chronic hepatitis D

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