North East and North Cumbria
ICS Formulary
 
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5 Infections
05-01-13 Urinary-tract infections

Nitrofurantoin
Formulary
  • Note: Liquid presentations of nitrofurantoin are very expensive compared to
    other solid dosage formulation. Please consider whether capsules can be used.
Link  MHRA Drug Safety Update (April 2023): Nitrofurantoin: reminder of the risks of pulmonary and hepatic adverse drug reactions
Link  MHRA Drug Safety Update (Feb 2015): Nitrofurantoin now contraindicated in most patients with an estimated glomerular filtration rate (eGFR) of less than 45 ml/min/1.73m2

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Methenamine Hippurate
Formulary
  • Approved as second line agent for prophylaxis in patients with recurrent UTI’s who have failed long-term antibiotic prophylaxis, have contraindications to antibiotics or breakthrough infection with resistant organisms.

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