Sunderland Joint Formulary
NHS Sunderland Clinical Commissioning Group
South Tyneside and Sunderland NHS Foundation Trust

 
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4 Central nervous system

As psychiatric services are provided by Northumberland, Tyne and Wear NHS Foundation Trust (NTW) the drugs available for Sections 4.1, 4.2, 4.3 and 4.4 are those listed in the Formulary used by NTW which is the North of Tyne Formulary

04-02-01 Second-Generation Antipsychotic Drugs

Risperidone
First Choice
Tablets: 500 microgram, 1mg, 2mg, 3mg, 4mg, 6mg
Oral liquid: 1mg/1ml
Orodispersible tablets: 500 microgram, 1mg, 2mg (Quicklets )
N.B. The dispersible tablets should only be used in situations where the plain tablets are unsuitable

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Amisulpride
Second Choice
Tablets: 50mg, 200mg
Oral solution: 100mg/1ml

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Aripiprazole
Formulary
Tablets: 5mg, 10mg, 15mg, 30mg

Orodispersible tablets: 10mg, 15mg
- for doses over 5 mg for those patients who have difficulty swallowing

Oral solutions: 1mg/1ml
- only for doses of 5 mg or less, or when titrating patients on doses of increments of less than 5 mg, in patients who have difficulty swallowing tablets
Link  NICE TA 213: Aripiprazole for the treatment of schizophrenia in people aged 15 -17 years
Link  NICE TA 292: Bipolar disorder (children) - aripiprazole
 

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Aripiprazole
Formulary
IM Injection: 7.5mg/ml
- approved for use in rapid tranquilisation in patients with acute psychosis. NTW use only

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Clozapine
Formulary
Tablets: 25mg, 100mg
First choice in patients with treatment-resistant schizophrenia
Contact NTW pharmacy department for continued supplies of clozapine during admission and on discharge

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Olanzapine
Formulary
Tablets: 2.5mg, 5mg, 7.5mg, 10mg, 15mg, 20mg
Orodispersible tablets: 5mg, 10mg, 15mg
N.B. The orodispersible tablets should only be used in situations where the plain tablets are unsuitable

10mg injection
- For rapid control of agitation and disturbed behaviours in patients with schizophrenia or manic episode, when oral therapy is not appropriate.
- The orodispersible tablets and injection are also approved for 2nd/3rd line use in the management of delirium in critical care patients unlicensed indication.

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Quetiapine
Formulary

Tablets: 25mg, 100mg, 150mg, 200mg, 300mg
Prolonged release tablets: 50mg, 150mg, 200mg, 300mg, 400mg
– this formulation is only approved for use in patients who require an outside carer to administer their medicines, and for short term use when rapid dose titration is considered important e.g. where its use might avoid the need to admit the patient to hospital


 


(note: preferred brand of quetiapine XL in primary care is Biquelle XL)


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Lurasidone Latuda®
Non Formulary

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Sertindole Serdolect®
Non Formulary

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Ziprasidone Zeldox®
Non Formulary

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Zotepine Zoleptil®
Non Formulary

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