North East and North Cumbria
ICS Formulary
 
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2 Cardiovascular system
02-03-02 Supraventricular and ventricular arrhythmias

Amiodarone
Formulary
  • 100mg & 200mg tablets Amber
  • 50mg in 5ml suspension is also approved Amber unlicensedunlicensed
  • 150mg/3ml & 300mg/10ml injection Red Traffic Light

NHS England (June 2019) advises that prescribers should not initiate amiodarone in primary care for any new patient.

in exceptional circumstances, where there is a clinical need for amiodarone to be prescribed, this should be undertaken in a cooperation arrangement with a multi-disciplinary team and/or other healthcare professional. Amiodarone has an important place in the treatment of severe cardiac rhythm disorders where other treatments either cannot be used or have failed. It has potential major toxicity and its use requires monitoring both clinically and via laboratory testing. 

MHRA Drug Safety Update (Mar 2022): Amiodarone (Cordarone X): reminder of risks of treatment and need for patient monitoring and supervision

Link  NENC Shared Care Protocol - Amiodarone for patients in adult services

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Atenolol
Formulary

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Flecainide
Formulary
  • 50mg & 100mg tablets
  • 5mg in 1ml liquid unlicensedunlicensed. 

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Propafenone
Formulary

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Disopyramide
Formulary

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Dronedarone
Formulary
  • Approved for patients who are unsuitable for or not tolerant of amiodarone. Treatment should be initiated by a cardiologist.
Link  NENC Shared Care Protocol - dronedarone for patients in adult services
Link  NICE TA197 (Atrial fibrillation - dronedarone)

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Flecainide Injection
Formulary
  • Injection: 150ml/15ml 

Red View adult BNF  View SPC online  View childrens BNF
Mexiletine
Formulary

  • unlicensed unlicensed

  • ECG monitoring is required to be carried out by as part of the initiation process of mexiletine.


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Sotalol
Formulary

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Ajmaline
Formulary
  • For use as a diagnostic test of Brugada syndrome.

Red