North East and North Cumbria
ICS Formulary
ICS Formulary
1 Gastro-intestinal system
01-05-03 Drugs affecting the immune response
| Azathioprine |
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Formulary
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 South Tyneside & Sunderland APC Shared Care Guideline - Azathioprine and Mercaptopurine in Gastroenterology |
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| Ciclosporin |
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Formulary
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County Durham and Darlington Shared Care Guideline: Ciclosporin |
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| Etrasimod Velsipity® |
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Formulary
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NICE TA956: Etrasimod for treating moderately to severely active ulcerative colitis in people aged 16 and over |
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| Filgotinib Jyseleca® |
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Formulary
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MHRA Drug Safety Update April 2023: Janus kinase (JAK) inhibitors: new measures to reduce risks of major cardiovascular events, malignancy, venous thromboembolism, serious infections and increased mortality NICE TA792: Filgotinib for treating moderately to severely active ulcerative colitis |
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| Upadacitinib Rinvoq® |
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Formulary
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MHRA Drug Safety Update April 2023: Janus kinase (JAK) inhibitors: new measures to reduce risks of major cardiovascular events, malignancy, venous thromboembolism, serious infections and increased mortality NICE TA856: Upadacitinib for treating moderately to severely active ulcerative colitis NICE TA905: Upadacitinib for previously treated moderately to severely active Crohn’s disease |
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| Methotrexate |
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Formulary
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County Durham and Darlington Shared Care Guideline: Methotrexate MHRA Drug Safety Update (Sept 2020): Methotrexate once weekly for autoimmune diseases: new measures to reduce risk of fatal overdose due to inadvertent daily instead of weekly dosing |
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| Vedolizumab |
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Formulary
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NICE TA352: Vedolizumab for treating moderately to severely active Crohn’s disease after prior therapy NICE TA342: Vedolizumab for treating moderately to severely active ulcerative colitis NICE TA826: Vedolizumab for treating chronic refractory pouchitis after surgery for ulcerative colitis (terminated appraisal) |
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Links
Newcastle, North Tyneside, Northumberland & Gateshead - Guidelines for Monitoring of Immune Modifying Drugs (IMDs) in Stable Adult Patients (excluding post transplantation) in Primary and Secondary Care- County Durham and Darlington Shared Care Guideline: 6-Mercaptopurine
- County Durham and Darlington Shared Care Guideline: Ciclosporin
- County Durham and Darlington Shared Care Guideline: Methotrexate
- County Durham and Tees Valley Guidance for Prescribing and Monitoring in Post Bariatric Surgery in Primary Care
- Guidelines for the Management of Adults with Asymptomatic Liver Blood Test Abnormalities
- MHRA Drug Safety Alert March 2020: Tofacitinib (Xeljanz▼): new measures to minimise risk of venous thromboembolism and of serious and fatal infections
- MHRA Drug Safety Alert Oct 2021: Tofacitinib (Xeljanz▼): new measures to minimise risk of major adverse cardiovascular events and malignancies
- MHRA Drug Safety Update (April 2023): Janus kinase (JAK) inhibitors: new measures to reduce risks of major cardiovascular events, malignancy, venous thromboembolism, serious infections and increased mortality
- MHRA Drug Safety Update (Jan 2015): Ustekinumab (Stelara): risk of exfoliative dermatitis
- MHRA Drug Safety Update (Sept 2020): Methotrexate once weekly for autoimmune diseases: new measures to reduce risk of fatal overdose due to inadvertent daily instead of weekly dosing
- MHRA Drug Safety Update April 2023: Janus kinase (JAK) inhibitors: new measures to reduce risks of major cardiovascular events, malignancy, venous thromboembolism, serious infections and increased mortality
- MHRA Drug Safety Update April 2023: Janus kinase (JAK) inhibitors: new measures to reduce risks of major cardiovascular events, malignancy, venous thromboembolism, serious infections and increased mortality
- MHRA Drug Safety Update May 2019: Tofacitinib (Xeljanz▼): restriction of 10 mg twice-daily dose in patients at high risk of pulmonary embolism while safety review is ongoing
- NICE CG61: Irritable bowel syndrome in adults: diagnosis and management
- NICE NG129: Crohn’s disease: management
- NICE NG130: Ulcerative colitis: management
- NICE NG147: Diverticular disease: diagnosis and management
- NICE TA 828: Ozanimod for treating moderately to severely active ulcerative colitis
- NICE TA163: Ulcerative colitis (acute manifestations) Infliximab
- NICE TA187: Crohn’s disease - infliximab and adalimumab
- NICE TA187: Crohns disease - infliximab & adalimumab
- NICE TA329: Infliximab, adalimumab and golimumab for moderately to severely active ulcerative colitis
- NICE TA329: Infliximab, adalimumab and golimumab for moderately to severely active ulcerative colitis
- NICE TA329: Infliximab, adalimumab and golimumab for moderately to severely active ulcerative colitis
- NICE TA342: Vedolizumab for treating moderately to severely active ulcerative colitis
- NICE TA352: Vedolizumab for treating moderately to severely active Crohn’s disease after prior therapy
- NICE TA456 Ustekinumab for moderately to severely active Crohn’s disease after previous treatment
- NICE TA547: Tofacitinib for moderately to severely active ulcerative colitis
- NICE TA633: Ustekinumab for treating moderately to severely active ulcerative colitis
- NICE TA792: Filgotinib for treating moderately to severely active ulcerative colitis
- NICE TA826: Vedolizumab for treating chronic refractory pouchitis after surgery for ulcerative colitis (terminated appraisal)
- NICE TA856: Upadacitinib for treating moderately to severely active ulcerative colitis
- NICE TA888: Risankizumab for previously treated moderately to severely active Crohn’s disease
- NICE TA905: Upadacitinib for previously treated moderately to severely active Crohn’s disease
- NICE TA925: Mirikizumab for treating moderately to severely active ulcerative colitis
- NICE TA938: Dupilumab for treating eosinophilic oesophagitis in people 12 years and over (terminated appraisal)
- NICE TA956: Etrasimod for treating moderately to severely active ulcerative colitis in people aged 16 and over
- North of Tyne, Gateshead and North Cumbria - Management of patients, post-bariatric surgery in primary care
- NTAG recommends the use of infliximab biosimilars as an option where the originator product (Remicade®) would normally be prescribed
- NTAG: Transanal irrigation (TAI) systems (Peristeen Plus®, Aquaflush®, and QuFora®) for neurogenic bowel dysfunction, chronic constipation and chronic faecal incontinence
- South Tyneside & Sunderland APC Shared Care Guideline - Azathioprine and Mercaptopurine in Gastroenterology
- South Tyneside & Sunderland APC Shared Care Guideline - Azathioprine and Mercaptopurine in Gastroenterology