North East and North Cumbria
ICS Formulary
 
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1 Gastro-intestinal system
01-05-01 Aminosalicylates

Mesalazine
Formulary

First Choice

  • Octasa MR® (400mg e/c m/r tablets): approved as first choice 400mg e/c m/r preparation for all new patients. Patients receiving Asacol® and Mesren® should be switched to Octasa® when appropriate. 800mg & 1600mg e/c m/r tablets also approved for suitable patients - to reduce tablet burden.
  • Asacol® (400mg e/c m/r tablets) - to be used for existing patients who are unable to change to Octasa MR®.
  • Pentasa® (500mg & 1000mg m/r tablets).
  • Mezavant® XL (1.2g e/c m/r tablets).
  • Salofalk® (500mg, 1000mg, 1500mg & 3000mg m/r granules/sachet) - only to be used in patients with difficulty in swallowing.

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Balsalazide Sodium
Formulary

Alternatives


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Mesalazine Rectal Preparations
Formulary
  • 500mg & 1g suppositories
  • 1g in 100ml retention enema, 2g in 59ml enema
  • 1g foam enema

 


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Sulfasalazine
Formulary
Link  County Durham and Darlington - Sulfasalazine shared care guideline
Link  North of Tyne, Gateshead and North Cumbria - Monitoring of Immune Modifying Drugs (IMDs) in Stable Adult Patients (excluding post transplantation) in Primary and Secondary Care shared care guideline
Link  South Tyneside and Sunderland APC Shared Care Guideline - sulfasalazine
Link  Tees Valley Shared Care Guideline - sulfasalazine

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