North East and North Cumbria
ICS Formulary
 
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1 Gastro-intestinal system
01-04-02 Antimotility drugs

Loperamide
First Choice
  • 2mg tablets and capsules
  • 2mg orodispersible tablets: approved for use in patients with high output stoma only when crushing tablets or opening capsules has failed. Also apporved for oral cancer patients struggling to take capsules Restricted Item Green plus
Link  MHRA Drug Safety Alert Sept 2017: Loperamide (Imodium): Reports of serious cardiac adverse reactions with high doses of loperamide associated with abuse or misuse

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Teduglutide Revestive®
Formulary
  • Approved for treating short bowel syndrome in people 1 year and above in line with NICE
Link  NICE TA804: Teduglutide for treating short bowel syndrome

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Codeine
Formulary
Link  MHRA Drug Safety Update (Dec 2014): Codeine for analgesia: restricted use in children because of reports of morphine toxicity
Link  MHRA Drug Safety Update (Dec 2014): Codeine: very rare risk of side-effects in breastfed babies

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