North East and North Cumbria
ICS Formulary
 
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6 Endocrine system
06-01-02-03 SGL2 inhibitors

Canagliflozin
Formulary
  • Only approved for use in accordance with NICE guidance. 
Link  NICE TA315: Canagliflozin for type 2 diabetes
Link  NICE TA390: Canagliflozin, dapagliflozin and empagliflozin as monotherapies for treating type 2 diabetes

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Dapagliflozin Forxiga®
Formulary
  • 5mg and 10mg tablets
    • Approved for treating type 2 diabetes in adults Green  
    • Approved for the treatment of chronic kidney disease in adults in line with NICE and NTAG Green

 

Link  NICE TA288: Dapagliflozin in combination therapy for treating type 2 diabetes
Link  NICE TA390: Canagliflozin, dapagliflozin and empagliflozin as monotherapies for treating type 2 diabetes
Link  NICE TA418: Dapagliflozin in triple therapy for treating type 2 diabetes
Link  NICE TA775: Dapagliflozin for treating chronic kidney disease

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Empagliflozin
Formulary
  • Approved in combination therapy for treating type 2 diabetes in line with NICE 
  • Approved for the treatment of type 2 diabetes in line with NICE 
  • Approved for treating chronic kidney disease in line with NICE
Link  NICE NG18: Diabetes (type 1 and type 2) in children and young people: diagnosis and management
Link  NICE TA336: Empagliflozin for type 2 diabetes
Link  NICE TA390: Canagliflozin, dapagliflozin and empagliflozin as monotherapies for treating type 2 diabetes
Link  NICE TA942: Empagliflozin for treating chronic kidney disease

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Ertugliflozin
Formulary
  • Approved as monotherapy or with metformin for the treatment of type 2 diabetes in line with NICE

 

Link  NICE TA572: Ertugliflozin as monotherapy or with metformin for treating type 2 diabetes
Link  NICE TA583: Ertugliflozin with metformin and a dipeptidyl peptidase-4 inhibitor for treating type 2 diabetes

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Sotagliflozin
Formulary
  • 200mg tablet
    • Approved with insulin for treating type 1 diabetes in adults with a body mass index (BMI) of at least 27 kg/m2, when insulin alone does not provide adequate glycaemic control despite optimal insulin therapy in line with NICE

 

Link  NICE TA622: Sotagliflozin with insulin for treating type 1 diabetes

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