North East and North Cumbria
ICS Formulary
 
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5 Infections
05-01-07 Linezolid

Linezolid Infusion
Formulary
  • IV infusion: 600mg/300ml

 

  • Restricted for use on microbiology/infectious diseases advice, or as agreed in Trust Guidelines.
Link   MHRA Drug Safety Update (Dec 2014): Linezolid: restricted indication

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Linezolid Oral Preparations
Formulary
  • 600mg tablets
  • 100mg in 5ml suspension

 

To be used only on the advice of a Consultant Microbiologist for resistant Gram-positive infections.

Patients must have weekly bloods taken to monitor for haematological side effects if receiving treatment for more than 10 to 14 days. In those receiving treatment for more than 4 weeks a pre-treatment eye assessment is recommended followed by monthly assessments. Patients should be warned to report any visual symptoms promptly (see BNF for CSM warning).

Linezolid is a MAO inhibitor and so potentially life threatening interactions can occur. Check before prescribing.

Link  MHRA Drug Safety Update (Dec 2014): Linezolid: restricted indication

Red View adult BNF  View SPC online  View childrens BNF
Linezolid Oral Preparations
Formulary
  • 600mg tablets
  • 100mg in 5ml suspension

 

To be used only on the advice of a Consultant Microbiologist for resistant Gram-positive infections.

RED drug for courses greater than 14 days  Red Traffic Light

Patients must have weekly bloods taken to monitor for haematological side effects if receiving treatment for more than 10 to 14 days. In those receiving treatment for more than 4 weeks a pre-treatment eye assessment is recommended followed by monthly assessments. Patients should be warned to report any visual symptoms promptly (see BNF for CSM warning).

Linezolid is a MAO inhibitor and so potentially life threatening interactions can occur. Check before prescribing.

Link  MHRA Drug Safety Update (Dec 2014): Linezolid: restricted indication

Green plus View adult BNF  View SPC online  View childrens BNF